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Compare this to oral administration: even if 20% of the dose survives first-pass metabolism, peak plasma levels occur 6090 minutes post-ingestion, and the concentration curve is flatter and more prolonged
Hydroxocobalamin is the standard UK preparation, administered intramuscularly for conditions like pernicious anaemia and gastrointestinal malabsorption B12 acts as a cofactor in DNA synthesis, red blood cell formation, and nervous system function, supporting energy metabolism pathways Common side effects include injection site reactions, mild gastrointestinal upset, and temporary urine discolouration, with serious reactions being rare NHS access requires GP assessment with blood tests
Its virtually painless, and we train you on proper technique
Cheeran MC, Lokensgard JR, Schleiss MR
One major advantage of intramuscular injection is that its increasingly effective at raising blood levels of B12
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