triple antagonist glp-1 Schematic illustration of monoagonists, dual agonists and Discovery of a potent and

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However, these agents exhibited notable drawbacks, such as dose-dependent thrombocytopenia, variable therapeutic efficacy, and the emergence of resistance mechanisms

5.4 Gastrointestinal Side Effects and Nutrient Loss Nausea and vomiting are well-documented adverse effects. Persistent vomiting or diarrhoea may: Increase electrolyte loss Reduce caloric intake Reduce dietary diversity However: These effects are typically transient and dose-related

in patients with T2DM ( Furthermore, a preclinical study conducted by Finan et al

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