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For chronic weight management as an adjunct to a reduced-calorie diet and increased physical activity for adults and pediatric patients aged 12 years and older with body weight greater than 60 kg and obesity, and for adults with overweight in the presence of at least one weight-related comorbid condition

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People enrolled in a study should also follow the study teams reporting instructions for adverse events

Practical strategies include starting gradually with spice levels, eating smaller portions earlier in the day, and keeping a food diary to identify personal triggers