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They're medically necessary." If you encounter resistance: "I'd like to speak to a supervisor, please." Most interactions won't require anything beyond the first sentence

[1] [2] Many patients and healthcare professionals have questioned whether this medication can affect heart rate

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This triple mechanism distinguishes retatrutide from existing approved weight loss peptides such as semaglutide (a GLP-1 receptor agonist) and tirzepatide (a dual GIP/GLP-1 receptor agonist), although direct head-to-head trials comparing these agents have not been conducted, and comparative efficacy has not been established