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10.1016/s0047-6374(00)00224-4 78 SibiyaT.GhaziT.MohanJ.NagiahS.ChuturgoonA

In this regard, the finding of a recent study have indicated that a novel LND derivative, HYL001, can selectively target mitochondria and effectively inhibit cancer stem cells (CSC)(Table 5) [193]

Preclinical data show this additive-to-synergistic interaction: each pathway potentiates the other's pituitary response, producing larger GH pulses without proportionally increasing side effects

"The rodent data is compelling but cannot substitute for proper clinical development" 14