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Semin Hematol 1990

It also plays a role in protecting B12 from being destroyed by stomach acid, such as in the stomach and intestines.[ref] TCN2 (transcobalamin II, TCN2 gene): TCN2 is a B12 transport protein that moves vitamin B12 from the bloodstream into cells throughout the body

It was subsequently moved to the bone marrow, lymph nodes, and spleen

TMAO concentrations correlate positively with various pathological conditions, including cardiovascular disease, diabetes, cancer, autoimmune disorders, bone metabolic diseases, polycystic ovary syndrome, and autism, while showing a negative correlation with conditions such as dementia and IBD (171)

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