doi: 10.1080/07315724.2000.10718088

Product Attributes CAS # : 75921-69-6 Molecular Formula : C78H111N21O19 Sequence (AA) : Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 Molecular Weight : 1646.85 g/mol PubChem CID : 16132139 Half-Life : ~30-60 minutes (extended pigmentation effect lasts weeks) Synonyms : Afamelanotide, MT-I, MT-1, NDP-MSH, Scenesse, [Nle4, D-Phe7]-alpha-MSH Type : Synthetic research peptide (alpha-MSH analog, MC1R agonist) Research Focus : Skin Pigmentation & Photoprotection, Melanocortin Signaling Scientific References Afamelanotide for prevention of phototoxicity in patients with erythropoietic protoporphyria Human RCT | Regulatory Afamelanotide and narrowband UV-B phototherapy for the treatment of vitiligo Human RCT Photoprotection by melanocortin 1 receptor agonists Animal | In vitro Afamelanotide: a melanocortin analogue for photoprotection Observational | Animal The melanocortin-1 receptor: red hair and beyond In vitro | Observational Melanocortin 1 receptor signaling and skin pigmentation In vitro | Animal Scenesse (afamelanotide) European Medicines Agency assessment report Regulatory | Human RCT Included In The Box Every product arrives in a premium, custom-designed PEPTIDE.Power box , engineered for convenience, hygiene, and safe storage in your refrigerator

Laser therapy targets the pigmentation, breaking it down for your body to absorb
Current NICE guidance on GLP-1 receptor agonists for diabetes and obesity does not specifically address their use in people with Crohn's disease or other forms of IBD
Change history 26 August 2025 The original online version of this article was revised: Author name Sungsoon Fang has been corrected