Pathophysiology of chronic migraine: Insights from recent neuroimaging research
Whenever possible, this should be discouraged
Individuals who developed serious gastrointestinal complications, diagnosed optic nerve injuries, or other severe side effects after taking GLP-1 receptor agonist medications may qualify to pursue legal action
For example, early studies tended to use chronic high frequency constant-current stimulation, while some of the later studies used chronic intermittent constant-voltage stimulation (e.g., 185 Hz, 210 s, 15 min on, 26 h off [144])
In contrast, another GLP1R agonist , with a shorter half-life of around 13 hours (Liraglutide) achieved only 5.5% reduction in the same time span [22] , demonstrating that improving half-life can result in better outcomes