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Similarly, while niacinamide is generally well-tolerated, individuals with known sensitivities to B-vitamins or nicotinic acid derivatives should exercise caution
Liposomal formulations, commonly used for local and ocular delivery, may still be affected by particle size heterogeneity, suboptimal encapsulation efficiency, and difficulties in industrial-scale production (Khalil et al., 2020)
Cold Spring Harb Perspect Biol 13:a040584 Darlington LG, Forrest CM, Mackay GM, Smith RA, Smith AJ, Stoy N, Stone TW (2010) On the biological importance of the 3-hydroxyanthranilic acid:anthranilic acid ratio