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2 Materials and methods 2.1 Experimental animals Male C57BL/6J mice [specific-pathogen-free (SPF) grade], aged 810 weeks and weighing 2025 g, were obtained from the Laboratory Animal Center of Ningxia Medical University

Thymosin beta-4 demonstrates a broader range of influence due to its capacity to regulate DNA polymerase activity and promote protein synthesis, allowing for more extensive remodeling in complex injury models

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Ibutamoren demonstrated a 1.7-fold increase in GH over 24 hours and an 88% IGF-1 increase at four weeks