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In this review, we summarize the current existing literatures on NADPH metabolism, including its biological functions, regulatory mechanisms, and the corresponding therapeutic interventions directly or indirectly targeting NADPH metabolism in cancer

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Primary research areas Oxidative stress, detoxification and cellular redox research

Recent early phase clinical trials have demonstrated a higher percentage of MASH resolution in patients who were treated with GLP-1 agonists compared to placebo, although they have not yet shown a statistically significant improvement in fibrosis stage 9