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The plasma concentrations of 7,8-DHF followed a two-compartment model where there was an initial rapid distribution occurred within 30 min of the IP injection, followed by a slower terminal phase with a terminal half-life of 1 h (Figure 5A)

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However, our ability to produce glutathione naturally declines with age as cells become more prone to damage, which is where effective oral supplementation becomes vital to support this essential defence

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