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elegans strains carrying the variants equivalent to those identified in our patients: gbh-1(D72G) for p.Asp59Gly, gbh-1(G283R) for p.Gly263Arg, and gbh-1(G247Vfs6) for p.Gly227Valfs*6

These sleep changes are usually mild and linked to how the body adjusts to appetite and metabolic shifts, often improving as treatment stabilises under clinical guidance

For air travel, check current airline regulations as most require LiPos to be carried in hand luggage within specific capacity limits

5-Amino-1MQ powder should be stored at room temperature (15-25C) in an airtight container, protected from light and moisture

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