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We're not there yet with obesity or obesities

Survodutide : Phase 2 MASH trial (NEJM 2024) showed 62% MASH resolution at 4.8 mg vs 14% placebo

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In contrast, a 15-year case-control study [46] evaluated the outcomes of Roux-en-Y gastric bypass in patients with heterozygous LMP variants (including MC4R , LEPR , POMC , and PCSK1 )