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The role of adipose triglyceride lipase and cytosolic lipolysis in cardiac function and heart Failure

Individuals at higher risk include older adults with reduced stomach acid production, people with gastrointestinal conditions affecting absorption, strict vegans, and those taking medications like metformin or proton pump inhibitors

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This dual action, increasing fat breakdown while blocking fat formation, creates a metabolic environment that favors net fat loss even when caloric intake is not dramatically reduced