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Schematic structure of Telisotuzumab vedotin (ABBV-399) [3] In the bispecific antibody field, Johnson & Johnsons Amivantamab-vmjw has been approved for clinical use

It is a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, which may lead to enhanced weight loss and metabolic effects compared to single or dual agonists

Avoiding alcohol and smoking for at least 24 hours also reduces stress on the liver

Combined use of glimepiride with insulin or metformin may increase the potential for hypoglycemia

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