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In a randomized, double-blind, placebo- and positive-controlled three-period crossover thorough QTc study in 54 healthy adult subjects, there was a positive relationship between the length of the rate-adjusted QTc interval and serum sertraline concentration

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142 (Rome, 2018)

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The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) defines BED as occurring at least once weekly for three months, with associated features including eating more rapidly than normal, eating until uncomfortably full, eating when not physically hungry, and feelings of disgust or guilt afterward