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In response to various extrinsic and intrinsic factors, such as a sedentary lifestyle, obesity, hyperglycaemia, oxidative and ER stress and genetic and epigenetic reprogramming, the activation of inflammatory signalling pathways, such as the Jun N-terminal kinase (JNK) and nuclear factor- B (NF-B) pathways, induces the constitutive production of inflammatory mediators

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Animal studies confirm hydrogen water boosts antioxidant enzyme activity, such as superoxide dismutase, reducing cellular damage

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