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INDICATIONS AND DIAGNOSIS Diagnostic aspiration or therapeutic injection of the first metatarsophalangeal joint can be performed in the management of advanced osteoarthritis, rheumatoid arthritis, and other inflammatory arthritides such as gout, or for synovitis or an arthrosis such as turf toe. 2527 Turf toe, a painful ligamentous injury resulting from hyperextension of the first metatarsophalangeal joint, often occurs in football linemen

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Ongoing monitoring is important, as chelation can reduce essential minerals over time, which may require supplementation

Stockwell BR, Jiang X, Gu W (2020) Emerging mechanisms and disease relevance of ferroptosis

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