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Start your intake The Scientific Discovery Behind GLP-1 Medications GLP-1 was first identified in 1987 by Danish researcher Jens Juul Holst during research on intestinal hormones that influence insulin secretion after meals

Chen XW, He ZX, Zhou ZW, Yang T, Zhang X, Yang YX, et al

Oxidative stress and mitochondrial dysfunction Mitochondria are not only the primary site of ROS production but also major targets of oxidative stress

121 Risk mitigation strategies Effective management of gallbladder disease risk in patients undergoing GLP-1RAs therapy requires a comprehensive and individualized approach that integrates early risk stratification, patient education, lifestyle modifications, routine clinical follow-up, and targeted therapeutic interventions (Figure 3)

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