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In conclusion, our study demonstrates that GCGR mAb not only ameliorates hyperglycaemia but also increases functional beta cell mass in mouse models of type 2 diabetes, and that these effects are at least partly mediated via liver-derived FGF21

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[DOI] [PubMed] [Google Scholar] 3.Harrison D.G., Cai H., Landmesser U., Griendling K.K