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doi: 10.3945/ajcn.117.157834, 46

If the goal includes sustained metabolic benefits or ongoing joint protection during high-load activity, extending the protocol to 12 weeks or transitioning to a maintenance dose provides better long-term results

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Research has observed that GLP-1 receptor agonists may: Improve blood vessel flexibility Reduce oxidative stress Lower systemic inflammation that contributes to plaque formation Support healthier lipid metabolism Some large-scale clinical trials have demonstrated reduced cardiovascular events in patients using GLP therapieseven when weight loss was not the primary variable