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Furthermore, other d-chiro-Ins-dependent biochemical processes, such as the activation of several insulin-affecting proteins (insulin receptor substrate 2 IRS2, phosphoinositide 3-kinase PI3K, and protein kinase B/AKT) at both mRNA and total protein levels, and the downregulation of glycogen synthase kinase 3 beta promote the glycogen storage process

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Regulation of IGF-I function by proinflammatory cytokines: at the interface of immunology and endocrinology