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Targeting or combined with ferroptosis pathway to regulate the cerebral environment is a very advisable treatment at present, and the inhibition of ferroptosis is likely to provide a new strategy for the prevention of neuron death induced by IS

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Proven Cardiovascular Benefits Reduced major adverse cardiovascular events (MACE) Reduced heart failure risk Anti-atherosclerotic effects Blood pressure reduction Weight-mediated cardiometabolic improvement Semaglutide and liraglutide especially demonstrated major cardiovascular outcome benefits

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MiR-34a/sirtuin-1/foxo3a is involved in genistein protecting against ox-LDL-induced oxidative damage in HUVECs