1 Introduction At present, depression has become a major mental illness worldwide ( Bifidobacterium ), and depressive symptoms is more directly measurable (e.g., via SCFA levels, neurotransmitter concentrations) than the vague association between overall diet and mood ( The gut-brain axisa bidirectional communication network involving the central nervous system (CNS), enteric nervous system (ENS), and gut microbiotaprovides a key framework for understanding nutrition-microbiota-depression interactions ( Bifidobacterium ) in depressed patients ( 2 Methods 2.1 Literature search strategy This review followed a systematic approach aligned with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines ( Search databases: a systematic search will be conducted across four major databases: PubMed, Web of Science Core Collection, Embase, and Cochrane Library

The body adjusts to GLP-1 receptor agonist activity, and removing that activity abruptly is not the same as a planned discontinuation
These omega-3 fatty acids also play a crucial role in supporting normal brain and nervous system function, contributing to cognitive performance, mood regulation, and vision
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Metformin as a first-line treatment for type 2 diabetes, and Peters evolving interest in metformin as a geroprotective drug [22:00]