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Association of short-term change in leukocyte telomere length with cortical thickness and outcomes of mental training among healthy adults: a randomized clinical trial

Researchers have also linked altered barrier function to disorders including irritable bowel syndrome and food allergies, and the association between high permeability and inflammatory conditions is an active, legitimate area of study

It is important to clarify that, whereas population-level PRS models require formal effect-size modeling, linkage disequilibrium correction, ancestry calibration, and validation across large cohorts, the score used in this workflow is a functional polygenic score (PRS-F) designed for mechanistic, individual-level interpretation rather than for epidemiological prediction