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Molecular analysis of Wilson patients: direct sequencing and MLPA analysis in the ATP7B gene and Atox1 and COMMD1 gene analysis

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Phosphorylation of FOXA2 by AKT sequesters the modified protein from nuclei to cytoplasm, where it is ubiquitinated and degraded (187189), increasing the expression of airway mucin genes MUC5AC and MUC5B (180, 190, 191)

The study also showed accelerated recovery from doxorubicin chemotherapy