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doi: 10.1002/art.21975 29 RuthJHParkCCAminMALeschCMarotteHShahraraSet al

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The details of the PIONEER program, including study design and results, have been published and reviewed extensively, therefore only a brief overview is provided here [38, 39, 61, 62, 76,77,78,79,80,81,82]

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