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However, despite these encouraging preliminary findings, the current body of evidence is constrained by small sample sizes, heterogeneous study designs, and a lack of standardised imaging protocols, which collectively limit reproducibility and generalisability

Glutathione is an antioxidant whose production and quantity decrease with aging

Preliminary data from a phase 1b extension study (NCT05292911) involving 64 individuals with MRI-PDFF 10% and BMI 28 kg/m 2 demonstrated that 50%, 44%, and 60% of participants presenting baseline alanine aminotransferase (ALT) 30 IU/L reached combined MRI-PDFF reduction 30% and ALT reduction 17 IU/L at pemvidutide doses of 1.2, 1.8, and 2.4 mg, respectively, vs

Reductions in caloric intake are found across all body mass index (BMI) categories