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However, robust quantitative translation between administered experimental doses and plausible human internal burdens remains highly uncertain due to variability in exposure assessment assumptions, limited size-resolved data on internal PET burdens in humans (particularly for the nanoscale fraction), and methodological constraints in detecting and characterising sub-micrometre particles in complex biological matrices

The primary potential advantage of HCG over SERMs is that it does not require a functioning pituitary gland to work effectively

13 Although the cellular pathways required for protein s -cysteinylation are not fully elucidated (Fig