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Experimental infection of cell lines has also shown that the activities of antioxidant enzymes may decrease over time 18,19 and that chemical stimulation from reactive oxygen species may even induce an upregulation of antioxidant enzymes in order to counteract oxidative stress 17

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Clinical trials across various autoimmune diseases, such as SLE, RA, type 1 diabetes, and Primary Sjgren's Syndrome, have demonstrated that Low-dose IL-2 can safely and effectively induce stable Treg cell proliferation and restore immune balance, leading to improved disease activity (266271)

10.1093/brain/awu138 22 BarmadaS