Reciprocally, gut microbiota biotransform dietary components to produce various physiologically active metabolites, such as SCFAs, secondary bile acids, and indole derivatives, which enter the liver via the portal venous system and participate in host glucose and lipid metabolism as well as immune regulation ( The concept of the gut-liver-kidney nutritional metabolic axis has gradually emerged and received widespread attention in recent years
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Scientists accessed medical information for each study participant, including BMI, demographic data, diagnoses, and prescriptions
Conservative doses may fall below effective threshold for some individuals