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You can find quercetin throughout the plant kingdom

Quercetin-pretreated SK-N-MC cell was observed to alleviate Mn-induced neurotoxicity by improved cell viability and reduced LDH with remarkable up-regulation of HO-1/Nrf2 and down-regulation of NF-B pathways ( in vivo study has found that quercetin treatment significantly suppressed Mn-induced oxidative stress and neuroinflammation suggested by mediating antioxidant activities via apoptosis, iNOS/NF-B, and HO-1/Nrf2 pathways ( Drosophila model of AD, quercetin exhibits neuroprotective effects against A toxicity in the brain by regulating the protein expression of cyclin B (Kong et al., 2016)

Hoque R, Sohail M, Malik A et al

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