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Olpasiran and lepodisiran are GalNAc conjugates containing siRNAs that target the LPA gene, promoting RISC-mediated degradation of Apo(a) mRNA and preventing Lp(a) particle assembly in hepatocytes
In the aforementioned study evaluating the prevalence and impact of vitamin C deficiency in patients with IBD, patients with active disease (defined by an elevated C-reactive protein or calprotectin) were significantly more likely to have an abnormal vitamin C level ([CRP: 39.1% vs
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![Figure 7. [Structure of GLP-1 Receptor Agonists.]. - Endotext](https://www.ncbi.nlm.nih.gov/books/NBK279141/bin/pharmaco-agent-diab2-Image007.jpg)
