The specific knockout or inhibition of HDAC9 can alleviate G2/M phase arrest in renal epithelial cells, thereby reducing the expressions of pro-fibrotic cytokines (collagen I, collagen IV, vimentin, -SMA, and TGF-1), ultimately alleviating renal tubular injury and tubulointerstitial fibrosis
Co HKC, Wu CC, Lee YC, Chen SH (2024) Emergence of large-scale cell death through ferroptotic trigger waves
It also plays a vital role in the immune system, helps the liver process toxins, and even helps recycle other antioxidants like Vitamin C and Vitamin E
doi:10.1016/S0140-6736(09)60551-1
This can lead to an increase in overall energy levels and a reduction in fatigue