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PDT treatment may be utilized before surgery in order to streamline the surgical procedure or, more frequently, after margin-controlled surgery in cases where a low-risk BCC region remains and the morbidity from further surgery outweighs the risk of a potential recurrence after PDT [154, 155]

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Several studies have demonstrated that Nrf2 contributes to the anti-inflammatory process as well as increased cysteine production (needed to make glutathione for detoxing)

Discovery [edit] GPX4 was first discovered in biochemistry laboratories of the University of Padua, where it was described as an enzyme capable of protecting against peroxidation

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