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doi: 10.1016/j.jacc.2006.09.032

Vitamin B12 is essential, but if you eat meat, you wont automatically get enough and if youre vegan, it doesnt mean youll end up with a deficiency

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It is appreciated that other substituents may be present on the aryl ring, the benzyl carbon, the alkanoic acid, or the methylene bridge, including but not limited to hydroxy, alkyl, alkoxy, alkylthio, halo, and the like