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Direct injection into already damaged tissue causes additional trauma and may worsen the condition

However, several studies demonstrate that doses of up to 500 mg of forskolin per day failed to reduce appetite, decrease food intake or encourage weight loss in overweight individuals ( Side effects: Little is known about the potential side effects of Coleus forskohlii , though one study reported diarrhea and increased bowel movements ( Summary Forskolin seems to have little impact on appetite or weight loss