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As acetyl-CoA is a universal breakdown product of metabolic substrates, acetylcarnitine becomes the most abundant acylcarnitine species in tissues and blood, acting as a regulator of cellular substrate utilization

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While surveying the literature in preparation of this manuscript we have also noticed and reported an increasing interest in the role that GSTs play in neurodegeneration, where isozymes belonging to the family may be either up-regulated, mutated or absent, according to the different diseases

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