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The needles create temporary channels through the stratum corneum while the serum flows through the needle bore at the same time, bypassing the skin barrier that would otherwise block large molecules like peptides, growth factors, and high-molecular-weight hyaluronic acid

Funding This manuscript was supported by an unrestricted grant from Novo Nordisk S.p.A

Given that tirzepatide produces weight loss exceeding these thresholds in many patients, similar reproductive benefits may occur, though this requires further research

Unused funds may roll over within the plan period based on the organizations policy, but at the end of the plan year, they are returned to the employer

Smoking cessation can also be helpful