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and Europe to approve and broadly adopt GLP-1 therapy, with Japanese prescribers known for their comfort with GLP-1 in T2DM management

This identified the reduction in butyrate-producing taxa as a signature of gut microbiome shifts in type 2 diabetes

It is available only as a research compound and is a WADA prohibited substance

Respondents reported a strong desire to reduce the pill burden associated with treatment, or to be off medication entirely, for treatments to help resume normal living, such as the ability to eat without restrictions, for treatments with fewer unpleasant side effects (i.e., weight gain, hypoglycemia, gastrointestinal side effects) and which are less physically invasive (i.e., do not require an injection) and for treatments which can normalize/stabilize blood glucose levels, and improve hemoglobin A1c

Singh SK