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Rats were pretreated with icv scopolamine (70 nmol in 2 aCSF) 20 min prior to training followed 15 minutes later by an ip injection of dihexa in DMSO ( 1 %) at .05mg/kg, .25mg/kg, or .50mg/kg

Lancet 366 , 649659 (2005)

Because DSIPs main potential benefit is improving sleep, timing it prior to your bedtime makes intuitive sense

Effective sonosensitizer delivery by redox sensitive nanoparticles for prostate cancer sonodynamic therapy via amplifying oxidative stress and peroxidation